![]() Jet lag disorder is caused by a temporary mismatch between the timing of the sleep and wake rhythm generated by the endogenous circadian clock with that of the new time zones imposed timing of sleep and wake pattern and other behaviors, as well as the change in the light-dark cycle. The authors provide an update on the current understanding of jet lag disorder, including diagnostic criteria based on the ICSD-3, pathophysiology, and therapeutic approaches to minimize symptoms. Jet lag disorder may be partially preventable or treatable by understanding the basics of circadian rhythm physiology and its interactions with the sleep-wake cycle. Individuals crossing several time zones can experience jet lag disorder, which is characterized by symptoms of difficulty falling asleep and/or excessive daytime sleepiness, general malaise, and somatic complaints. In todays society, transmeridian air travel is a common mode of transportation.
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